Improving outcomes & quality through collaboration

Improving quality of care in pediatric cardiac surgery is complex. We describe using institutional The Society of Thoracic Surgery (STS) Congenital Heart Surgery Database (CHSD) data in real time to develop a quality framework with the aim of optimizing team performance and thus improving clinical outcomes.

Racial and ethnic disparities in neonatal postoperative outcomes are reported, but differences in cardiac surgery-associated acute kidney injury (CS-AKI) remain unexamined. We assessed racial/ethnic disparities in CS-AKI prevalence and outcomes in neonates undergoing congenital heart surgery.

ObjectiveThis study aimed to investigate associations between early diuretic administration following neonatal cardiac surgery and clinical outcomes.MethodsThis was a retrospective cohort study including neonates who underwent cardiac surgery within the first 30 postnatal days between September 2015 and January 2018 at 22 centers participating in the Pediatric Cardiac Critical Care Consortium (PC) and Neonatal and Pediatric Heart and Renal Outcomes Network (NEPHRON) registries. Multivariable logistic and ordinal regression models were used to assess associations between early diuretic administration [defined as receipt of furosemide in the operating room and/or any diuretic on postoperative day 0 (POD0)] and outcomes. Outcomes: peak cumulative fluid balance, delay in achieving first negative daily fluid balance, duration of mechanical ventilation, hospital length of stay (LOS), and severe persistent acute kidney injury (AKI). An additional exploratory analysis was performed to assess for association between receiving enteral diuretic within the study period (POD0-6) and hospital LOS.ResultsOf 2240 neonates, 63% (n = 1405) had early diuretic administration and 15% (n = 344) received enteral diuretics. After adjusting for covariates and center effect, early diuretic administration was associated with shorter duration of mechanical ventilation [Odds Ratio (OR) = 0.59, 95% confidence interval (95%CI) 0.42-0.82] and a lower odds of delay in negative daily fluid balance (OR = 0.44, 95%CI 0.26-0.75), but not severe persistent AKI. Receiving enteral diuretic by POD6 was associated with decreased hospital LOS (OR = 0.3, 95%CI 0.23-0.41).ConclusionsEarly diuretic administration is associated with earlier time to negative daily fluid balance and shorter duration of mechanical ventilation. Efforts to standardize early diuretic administration have the potential to decrease resource utilization and warrants further study.

ObjectiveChildren's HeartLink and the University of California San Francisco (UCSF) have partnered with Vietnam National Children's Hospital (VNCH). Compared with low- and middle-income countries (LMICs) enrolled in the International Quality Improvement Collaborative for Congenital Heart Disease, VNCH is a high performing center. Our goal is to compare outcomes of VNCH with North American centers leveraging data from the Pediatric Cardiac Critical Care Consortium (PC) in 2023.MethodsChildren's HeartLink established a partnership with VNCH in 2017 with a consistent senior-level medical volunteer team from UCSF (Dr Sano currently at Showa University Hospital) engaged in semiannual training visits and weekly case conferences. In-person visits have evolved to hands-off teaching. Areas of improvement are identified, and outcomes presented at the subsequent visit. International Quality Improvement Collaborative and PC perform site specific audits to confirm data accuracy. Data presented are based on primary operations. Conversion from Risk Adjustment for Congenital Heart Surgery (RACHS-1) to STAT is as follows: RACHS-1 1-4 equal STAT 1-4; RACHS-1 5-6 equal STAT 5.ResultsResults represent 8 on-site visits and 109 case discussions. VNCH performed 1,056 operations, and PC represents 14,506 operations in 2023. VNCH had comparable outcomes, except higher surgical mortality for infants with prematurity and noncardiac abnormalities, and a higher rate of surgical site infections. VNCH performed fewer operations on patients with noncardiac abnormalities and higher STAT scores.ConclusionsPartnership of highly resourced North American programs with underresourced LMIC centers can elevate congenital heart surgery outcomes. VNCH is a high-volume center with respectable outcomes. Future focus will be higher STAT level and neonatal surgeries.

Children undergoing surgery for congenital heart disease (CHD) are at risk for catheter-associated deep vein thrombosis (CA-DVT). We sought to understand the practice variations which may impact the risk for CA-DVT by conducting a comprehensive survey. Analysis of electronic survey of Pediatric Cardiac Critical Care Consortium (PC) hospitals caring for children undergoing surgery for CHD. Responses from 45 respondent PC4 centers was analyzed; 71% of centers (n = 32) had a prophylactic anticoagulation protocol. Two of the 45 respondent centers utilized a protocol for proactive screening for CA-DVT; 64% of centers (29/45) treated CA-DVT for a duration of 6 to 12 weeks. Internal jugular central vein catheters (CVC) were the most common primary access in children who were 1 to 18 years of age undergoing surgery (89% [40/45] of centers) and in infants 1 to 12 months of age (73% [33/45] of centers). Significant variability CVC-type selection was reported in neonates (<30 days of age). More than half of centers reported avoiding upper extremity peripherally inserted central catheter placement in patients both prior to and after stage 2 palliation for single ventricle CHD (58% [26/45] and 53% [24/45], respectively). Significant variability in prevention and management of CA-DVT is reported among PC centers. Only half of respondent PC4 centers reported having an established treatment protocol for CA-DVT. Consensus and evidence-based guidelines for the treatment of CA-DVT are not consistently followed with only 62% (28/45) of centers reported treating for the recommended 6 to 12 weeks with anticoagulation. There is high variability in CVC-type and location selection in neonates undergoing CHD surgery.